• Home
  • Contact Us!
  • Privacy Policy

Radio Metta

  • Home
  • Business
  • Education
  • Health
  • Home Deco
  • News
  • Real Estate
  • Technology
  • Contact Us!
  • Privacy Policy
Home» Health»Promising lab-grown skin sprouts hair and grows glands

Promising lab-grown skin sprouts hair and grows glands

Saheli 04 Apr 2016 Health Comments Off on Promising lab-grown skin sprouts hair and grows glands 219 Views

transplanted cells with hair growing from them

Scientists in Japan have successfully transplanted mice with lab-grown skin that has more of the organ’s working parts in place than ever before.

Starting with stem cells made from a mouse’s gums, they managed to craft skin with multiple layers – as well as hair follicles and sweat glands.

When implanted into a “nude mouse” with a suppressed immune system, it integrated well and sprouted hairs.

Researchers say this success will take 5-10 years to translate into humans.

But eventually, the team hopes their system will lead to perfectly functioning skin that can be grown from the cells of burns victims and transplanted back on to them.

Table of Contents

Toggle
  • Personalised organs
  • ‘Whole box of stuff’

Personalised organs

This would be vastly superior to the culturing and grafting techniques that are currently available, which produce skin without many of the the biological components and functionality that we are used to.

The technique could also be adapted to manufacture realistic skin samples that drug or cosmetics companies could use to test their products – instead of using animals.

The findings, reported in the journal Science Advances, have been greeted with enthusiasm by other scientists working in this field.

Takashi Tsuji is the paper’s senior author. He said the dream of re-growing personalised organs was beginning to materialise:

“Up until now, artificial skin development has been hampered by the fact that the skin lacked the important organs, such as hair follicles and exocrine glands, which allow the skin to play its important role in regulation.

“With this new technique, we have successfully grown skin that replicates the function of normal tissue.

“We are coming ever closer to the dream of being able to recreate actual organs in the lab for transplantation.”

skin samples sprouting hairImage copyrightTakagi et al / Science Advances
Image captionThe researchers saw the transplanted skin going through normal hair growth cycles

Dr Tsuji, from the Riken Centre for Developmental Biology in Kobe, conducted the research with colleagues in Tokyo, Sagamihara and Sendai.

They began their experiments by taking cells from the gums of a mouse and converting them into “induced pluripotent stem cells” or iPSCs.

It’s recapitulating normal skin architecture

Prof John Mcgrath, King’s College London

This is a popular and promising technique in stem cell research, discovered in 2006, which bathes the cells in chemicals to “wind back the clock”. The resulting cells, like those of an embryo, can divide again and again, and be guided down many developmental pathways to become nearly any type of cell in the body.

The team’s real achievement was in coaxing these cells to form the different layers and structures of deeply layered skin – the “integumentary organ” that protects our bodies, senses touch, regulates heat and does myriad other jobs as well.

‘Whole box of stuff’

John McGrath, a professor of molecular dermatology at King’s College London, said this study was one that researchers in his field had been looking out for – and it was a substantial step forward.

He told BBC News that the new system took us “over the halfway mark” towards growing functional skin for human patients – where previous efforts had stumbled at much earlier stages.

“It’s recapitulating normal skin architecture,” Prof McGrath said. “So rather than having isolated bits of skin… here we’ve actually got a whole box of stuff.

“To give you a football analogy: anybody can have Wayne Rooney, but now we’ve got Manchester United. There’s a whole team on the pitch, of interacting players.”

And that means there is hope, he added, for lifelike, lab-grown skin.

“[Today’s skin grafts] function, but they don’t really look like or behave like skin. If you don’t have the hair follicles and you don’t have the sweat glands and things, it’s not going to function as skin.”

Prof McGrath also said that many other laboratories would now be trying to reproduce these findings – and to adapt them for different purposes, such as recreating skin diseases in a dish and trying out treatments.

“There will be lots of benefits for immediate use, as well as for translational science,” he said.

[Source:- BBC news]

and glands grows hair lab-grown Promising skin sprouts 2016-04-04
Tags and glands grows hair lab-grown Promising skin sprouts
Facebook Twitter Stumble linkedin Pinterest More

Authors

Posted by : Saheli
Previous Article :

India objects to Obama clubbing India with Pak on nuclear security

Next Article :

New army launcher successfully fires Hellfire, Sidewinder missiles

Related Articles

MyChart: 8 Things You May Not Know You Can Do

MyChart: 8 Things You May Not Know You Can Do

admin 12 Mar 2025
Top Affordable Travel Insurance in 2025

Top Affordable Travel Insurance in 2025

admin 07 Mar 2025
Tips from a Specialist for World Psychological well-being Day

Tips from a Specialist for World Psychological well-being Day

admin 03 Oct 2024

Latest Post

Why some houses sell more quickly than others
Real Estate

Why some houses sell more quickly than others

admin 07 May 2025
Get AI Ready — What IT Leaders Need to Know and Do
Technology

Get AI Ready — What IT Leaders Need to Know and Do

admin 22 Apr 2025
Job Prospects in Real Estate: Is Real Estate a Good Career Path?
Real Estate

Job Prospects in Real Estate: Is Real Estate a Good Career Path?

admin 12 Apr 2025

Creating Spaces: Decor for Every Room in Your Home

admin 05 Apr 2025
Tips for staying safe online and tracking scams
Technology

Tips for staying safe online and tracking scams

admin 01 Apr 2025
Our testimony regarding the California Journalism Preservation Act to the Judiciary Committee of the California Senate
News

Our testimony regarding the California Journalism Preservation Act to the Judiciary Committee of the California Senate

admin 24 Mar 2025
EdTech Hub at CIES 2025
Education

EdTech Hub at CIES 2025

admin 19 Mar 2025
May 2025
M T W T F S S
 1234
567891011
12131415161718
19202122232425
262728293031  
« Apr    
  • Home
  • Contact Us!
  • Privacy Policy
Copyright 2016, All Rights Reserved
Magazine Blog News WordPress Theme